翻訳と辞書 Words near each other ・ Phosphofructokinase ・ Phosphofructokinase 1 ・ Phosphofructokinase 2 ・ Phosphofructokinase deficiency ・ Phosphoglucan, water dikinase ・ Phosphoglucokinase ・ Phosphoglucomutase ・ Phosphoglucomutase (glucose-cofactor) ・ Phosphoglucomutase 3 ・ Phosphogluconate 2-dehydrogenase ・ Phosphogluconate dehydratase ・ Phosphogluconate dehydrogenase ・ Phosphogluconate dehydrogenase (decarboxylating) ・ Phosphoglucosamine mutase ・ Phosphoglycerate ・ Phosphoglycerate dehydrogenase ・ Phosphoglycerate kinase ・ Phosphoglycerate kinase (GTP) ・ Phosphoglycerate mutase ・ Phosphoglycerate phosphatase ・ Phosphoglyceric acid ・ Phosphoglycerol geranylgeranyltransferase ・ Phosphoglycolate phosphatase ・ Phosphogypsum ・ Phosphohydroxypyruvic acid ・ Phosphoinositide 3-kinase ・ Phosphoinositide 3-kinase inhibitor ・ Phosphoinositide 5-phosphatase ・ Phosphoinositide phospholipase C ・ Phosphoinositide-dependent kinase-1 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Phosphoglycerate dehydrogenase ： ウィキペディア英語版 Phosphoglycerate dehydrogenase In enzymology, a D-3-phosphoglycerate dehydrogenase () is an enzyme that catalyzes the chemical reactions :3-phospho-D-glycerate + NAD+ $\backslash rightleftharpoons$ 3-phosphonooxypyruvate + NADH + H+ :2-hydroxyglutarate + NAD+ $\backslash rightleftharpoons$ 2-oxoglutarate + NADH + H+ Thus, in the first case, the two substrates of this enzyme are 3-phospho-D-glycerate and NAD+, whereas its 3 products are 3-phosphohydroxypyruvate, NADH, and H+; in the second case, the two substrates of this enzyme are 2-hydroxyglutarate and NAD+, whereas its 3 products are 2-oxoglutarate, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. In humans, this enzyme is encoded by the ''PHGDH'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26227 )〕 == Function == 3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.〔 Certain breast cancers are dependent on the overexpression of PHGDH. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Phosphoglycerate dehydrogenase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.